Peptide Database

Peptide NameBeta-defensin 17

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC340H543N93O88S8

DescriptionStandard

        MKFHLLFFILLFSITILTGKRSYPEYGSLDLRKECRMSKGHCKLQCSENEIRIAFCIRPGTHCCI
    

Molecular Weight7598.04 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)4.71

Net Charge (pH 7.4) 4.24

Charge Density (pH 7.0) 0.0724

GRAVY Index0.11

Hydrophobic Moment 0.50

Boman Index0.04

Instability Index53.51

Aliphatic Index 91.54

Aromaticity 0.1077

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2908.76

LogP -22.09

H-bond Donors 110.0

H-bond Acceptors 104.0

Rotatable Bonds 256.0

Heavy Atoms 529.0

Ring Count 12.0

Amide Bonds 66.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322643 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q32ZH5/entry; https://bblserver.org.in/ampdb/