Peptide Database

Peptide NameAndroctonus defensin

Function Ontology

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Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC106H167N41O28S4

DescriptionStandard

        GCPFNQGACHRHCLSIRRRGGYC
    

Molecular Weight2591.98 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)3.89

Net Charge (pH 7.4) 3.53

Charge Density (pH 7.0) 0.1693

GRAVY Index-0.60

Hydrophobic Moment 0.51

Boman Index-0.22

Instability Index117.16

Aliphatic Index 38.26

Aromaticity 0.0870

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1126.33

LogP -14.76

H-bond Donors 45.0

H-bond Acceptors 38.0

Rotatable Bonds 82.0

Heavy Atoms 179.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032074 VERIFIED: YES

Provenance & Taxonomy

OrganismRhipicephalus appendiculatus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)