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MYP_106605
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Basic Information
Dicynthaurin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C139H242N36O41S
Standard
Sequence
ILQKAVLDCLKAAGSSLSKAAITAIYNKIT
Physicochemical Analysis
3105.69 Da
9.52
2.75
2.52
0.0915
0.64
0.52
0.21
42.03
133.67
0.0333
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1256.16
-12.02
45.0
45.0
107.0
217.0
1.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0137421 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0190567 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID11479030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11479030/
RECORD: Rec_0202599 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
50 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/11479030/ PMID11479030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11479030/
RECORD: Rec_0208178 VERIFIED: NO
Provenance & Taxonomy
Sea peach [Animal]; Actinopterygii [Animal]
33208; 7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0223217 VERIFIED: YES
Provenance & Taxonomy
Halocynthia aurantium [Plant]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus(50 units at 100ug/ml)
PaperPubMed PMID: 11479030 PMID11479030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11479030/
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