Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC441H701N129O115S8

DescriptionStandard

        MPRIYERRKEGVVNFWAVGSGMASAENHCLNLSGICRRDICKITEDQIGACKRRWKCCRSWWILVPIPTPLIYSDYQAPLKHKLK
    

Molecular Weight9906.60 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)7.62

Net Charge (pH 7.4) 7.19

Charge Density (pH 7.0) 0.0896

GRAVY Index-0.33

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index61.37

Aliphatic Index 83.76

Aromaticity 0.0941

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3940.48

LogP -32.05

H-bond Donors 146.0

H-bond Acceptors 133.0

Rotatable Bonds 325.0

Heavy Atoms 693.0

Ring Count 19.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407867 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Tax ID9689

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal