Peptide Database

Peptide NameBeta-defensin 104A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC373H602N112O104S7

DescriptionStandard

        MRRLVLLLTISVLLYQDLPVRSEFEWDRICGYGTARCRNKCRSQEYRIGRCPNTFACCLRKWDESLLNSTKP
    

Molecular Weight8543.91 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0757

GRAVY Index-0.38

Hydrophobic Moment 0.63

Boman Index-0.17

Instability Index57.30

Aliphatic Index 85.28

Aromaticity 0.0972

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3551.00

LogP -33.51

H-bond Donors 135.0

H-bond Acceptors 117.0

Rotatable Bonds 283.0

Heavy Atoms 596.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269589 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence