Peptide Database

Peptide NameHMG-CoA reductase inhibitory peptide

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ HMG-CoA Reductase Inhibitory

Metabolic ▸ Lipid metabolism ▸ Lipid-lowering activity

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC18H24N4O7

DescriptionStandard

QDF

Molecular Weight408.41 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.4129

GRAVY Index-1.40

Hydrophobic Moment 0.74

Boman Index-0.19

Instability Index45.73

Aliphatic Index 0.00

Aromaticity 0.3333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 201.91

LogP -1.65

H-bond Donors 6.0

H-bond Acceptors 6.0

Rotatable Bonds 12.0

Heavy Atoms 29.0

Ring Count 1.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383788 VERIFIED: YES

Provenance & Taxonomy

OrganismVigna unguiculata [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory

TargetHMG-CoA reductase

Activity12.8 μM

MethodIC50

RECORD: Rec_0385737 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913.0