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MYP_106494
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C40H48N6O11
Standard
Sequence
AYFYPE
Physicochemical Analysis
788.84 Da
4.60
-1.20
-1.39
-0.1997
-0.52
0.14
0.28
112.20
16.67
0.5000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
277.79
0.35
9.0
10.0
19.0
57.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0319283 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant Macrophage-modulating
Caco-2 cells
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0372629 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0378602 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperMILK PROTEINS AS PRECURSORS OF BIOACTIVE PEPTIDES
RECORD: Rec_0422025 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
106 μM
IC50
PaperAntihypertensive effect of the peptides derived from casein by an extracellular proteinase from Lactobacillus helveticus CP790 PMID8201050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8201050/
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