Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC374H628N94O108S8

DescriptionStandard

        MKLLLLLLTVTLLLAQVTPVMKCWGKSGRCRATCKESEVYYILCKTEAKCCVDPKYVPVKPKLTDTNTSLESTSAV
    

Molecular Weight8426.07 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0585

GRAVY Index0.20

Hydrophobic Moment 0.62

Boman Index0.07

Instability Index16.53

Aliphatic Index 102.50

Aromaticity 0.0526

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3238.32

LogP -27.75

H-bond Donors 120.0

H-bond Acceptors 121.0

Rotatable Bonds 280.0

Heavy Atoms 584.0

Ring Count 9.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0190614 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0384258 VERIFIED: NO