Peptide Database

Peptide NameBig defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length117 amino acids

Chemical FormulaC583H893N159O158S8

DescriptionStandard

        MEKKTAYCLLFLVLLVPYTALGAVLKRAPAKKEKRAVPLAVPLVYWGASVSPAVWNWLLVTFGAAAVAAAAVTVSDNDSHSCANNRGWCRSRCFSHEYIDSWHSDVCGSYDCCRPRY
    

Molecular Weight12913.82 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.69

Net Charge (pH 7.4) 4.20

Charge Density (pH 7.0) 0.0401

GRAVY Index0.15

Hydrophobic Moment 0.56

Boman Index0.11

Instability Index41.76

Aliphatic Index 86.75

Aromaticity 0.1197

Extinction Coeff. Reduced 36440.00

Extinction Coeff. Oxidized 36815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5015.95

LogP -44.02

H-bond Donors 186.0

H-bond Acceptors 174.0

Rotatable Bonds 401.0

Heavy Atoms 908.0

Ring Count 28.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042958 VERIFIED: NO

Provenance & Taxonomy

OrganismBranchiostoma belcheri [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0301845 VERIFIED: NO