Peptide Database

Peptide NameSLAY-screened peptide P2409

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC51H82N18O16S

DescriptionStandard

        PRITAHDAMHS
    

Molecular Weight1235.37 Da

Isoelectric Point (pI)7.33

Net Charge (pH 7.0)0.13

Net Charge (pH 7.4) -0.03

Charge Density (pH 7.0) 0.0122

GRAVY Index-0.68

Hydrophobic Moment 0.19

Boman Index-0.10

Instability Index46.59

Aliphatic Index 53.64

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 537.35

LogP -6.45

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 38.0

Heavy Atoms 86.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011537 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/