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MYP_106447
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Basic Information
HPAB-beta (a hBD-2 variant; beta-defensins)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C184H303N55O50S6
Standard
Sequence
GDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKPN
Physicochemical Analysis
4278.10 Da
9.30
5.78
5.43
0.1446
-0.29
0.52
-0.05
45.22
56.00
0.0500
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1661.48
-18.83
62.0
63.0
135.0
295.0
8.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0022020 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter lwoffii
62.5 μg/mL
MIC
PMID15808901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15808901/
RECORD: Rec_0045580 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae
62.5 μg/mL
MIC
PMID15808901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15808901/
RECORD: Rec_0124074 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
31.25 μg/mL
MIC
PMID15808901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15808901/
RECORD: Rec_0131122 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella dysentery
62.5 μg/mL
MIC
PMID15808901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15808901/
RECORD: Rec_0136466 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus feces ATCC 29212
250 μg/mL
MIC
PMID15808901 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15808901/
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