Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length176 amino acids

Chemical FormulaC834H1335N251O250S12

DescriptionStandard

        MANLKTKLSAAMLALIAAGASAPVLMDQFLNEKEGNSLTSYRDGAGIWTICRGATRVDGRPVTQGMNLTQTKCDQVNAVERNKALAWVDQNVRVPLTPPQKVGIASFCPYNIGPGKCFPSTFYRKLNAGDRKGACAEIRRWIFDGGKDCRVRSNNCYGQVSRRDQESALACWGIDE
    

Molecular Weight19262.83 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.07

Charge Density (pH 7.0) 0.0423

GRAVY Index-0.35

Hydrophobic Moment 0.73

Boman Index-0.06

Instability Index36.70

Aliphatic Index 73.24

Aromaticity 0.0739

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8136.03

LogP -92.84

H-bond Donors 290.0

H-bond Acceptors 270.0

Rotatable Bonds 638.0

Heavy Atoms 1347.0

Ring Count 25.0

Amide Bonds 194.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008675 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyLysozyme

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0031029 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage ST405-OXA48phi1.2 [Virus]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0271969 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae 909957 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence