Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length433 amino acids

Chemical FormulaC2176H3411N583O611S10

DescriptionStandard

        THPGFVARITQAGLDYAHQQGIAILEEELAQLKLPDISGDFRIRHVGKVHYEISRLDLRSFQLPYSRISLVPNVGLQVSISNAFAELDGNWRVKIHFIRDHGSFDLKVENIYIKISLKLGNDASGKPTIDTSDCSTRISKVRVHFSGKFGWLYNLFHSAIESRFRKTLESKVCMNVVSSVHSELQPYLQTLPVTANIDAMAGIDYSLVAPPTATANALDVDLKGEFFSLSHRSAVPFSPVALAFPPDHDRMVYFAASSYFFNTAGFAYHAAGALVFEITDSMIPKDLEFHLRTSTFSAFVPQLEKMYPDMPMKLRLSAPSAPFLNIGPGGLSLKPVVDVQAYAILPNSTLAPLFLLSLVSNVSAVIDIKSSHIVGNLNVGRYGGRAVRTLQSVMNILASSILLPRLNARLDQGFPLPLLDRIQLSNTLVRFHQ
    

Molecular Weight47835.55 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.72

Net Charge (pH 7.4) 3.66

Charge Density (pH 7.0) 0.0109

GRAVY Index0.11

Hydrophobic Moment 0.90

Boman Index0.12

Instability Index41.53

Aliphatic Index 102.47

Aromaticity 0.0947

Extinction Coeff. Reduced 30370.00

Extinction Coeff. Oxidized 30495.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370644 VERIFIED: NO

Provenance & Taxonomy

OrganismScopus umbretta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria