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MYP_106393
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Basic Information
Unnamed
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Venom / Toxin ▸ Toxin
Standard
14 amino acids
C73H125N19O16S
Standard
Sequence
INWKGIAAMAKKLL
Physicochemical Analysis
1556.96 Da
10.30
2.76
2.55
0.1969
0.53
0.56
0.24
-7.50
132.86
0.0714
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
578.56
-1.68
20.0
20.0
54.0
109.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0183587 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0191294 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Mastoparan
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 2592
3.7 μg/mL
MIC
PMID16330062 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
RECORD: Rec_0230831 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID16330062;17046111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
RECORD: Rec_0247849 VERIFIED: YES
Provenance & Taxonomy
Wasp [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
-H
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Active against Staphylococcus aureus
PMID35425831 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35425831/
RECORD: Rec_0249431 VERIFIED: YES
Provenance & Taxonomy
Vespa magnifica [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
rabbit red blood cells
PMID16330062;17046111 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16330062/
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