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MYP_106350
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Basic Information
Ixosin (4-23)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C118H187N33O29S
Standard
Sequence
KVMREVLGYERNSYKKFFLR
Physicochemical Analysis
2564.02 Da
10.16
3.76
3.55
0.1880
-0.80
0.62
-0.31
9.27
68.00
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1058.36
-6.45
39.0
34.0
89.0
181.0
4.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0255643 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa[10-20% Killing = 128 microM
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0289459 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
μM
128 μM
Cytotoxicity
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0382067 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0403284 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PAO1
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
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