Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length186 amino acids

Chemical FormulaC938H1487N255O252S7

DescriptionStandard

        PKTLPTAHEPMLLLAVTELVANSAAFTYFTAGALHRTLSSDMLPRRFPFQLRTKSMKVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPELPQGLPVLQVKHLETVLKFGLWLFGVPQANSKCCPRPVP
    

Molecular Weight20592.85 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)6.47

Net Charge (pH 7.4) 6.03

Charge Density (pH 7.0) 0.0348

GRAVY Index-0.01

Hydrophobic Moment 0.56

Boman Index0.09

Instability Index50.17

Aliphatic Index 94.89

Aromaticity 0.0753

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7943.66

LogP -91.40

H-bond Donors 271.0

H-bond Acceptors 271.0

Rotatable Bonds 648.0

Heavy Atoms 1452.0

Ring Count 43.0

Amide Bonds 200.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0411137 VERIFIED: NO

Provenance & Taxonomy

OrganismLeucopsar rothschildi (Bali myna) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria