Peptide Database

Peptide NameColicin-E3 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length516 amino acids

Chemical FormulaC2457H3806N698O753S18

DescriptionStandard

        MASVNRGCTVHGKNVGLHGDKTSTGAQCIAARPGMSVMGKLKLYIGDKTTPCPKCGEVGVIITGDHRQTNGEAVAVDGSVIHCDCPMGSNFLIAPGTVQVNDPFGVLEPPVNKAAAAAAAAAAAAMSALPVFAKSCLRGEGCTDAGTDQESVDNFGHAGYYCATPQAEQPEEEPVQHAQAAKKHKPAEPTPPPEDNRPWYKRLFSSPDTTKAAVTAGTATARAATTAGITTGATTEAGYATLQKIGGNLTAAGRWITPNPSTVFLFGMFYSPKLNSGEQDYIDRMRLEQAAQKKEDVPTRVRFRWEADQYGTMRPKGFHVSARGGRDKVPVRMLQKNTTTGNYEFWEDGATKPIIVWTPDDPGYASPSNTGKQDNVYIPPNVLVYPESEIDSPWSTETPAPGERSFRDYILVHPAGIFDPVYIYLNAAHKYHTPPKENPPLPAFPDAKKAQAKTPVKGGGKLRNRWKDSEGKIYEWDSQHGTVEVYDRSGRNHLGEFNHITGEQTKPANPTRKVEK
    

Molecular Weight55747.90 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)2.69

Net Charge (pH 7.4) 1.49

Charge Density (pH 7.0) 0.0052

GRAVY Index-0.60

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index41.55

Aliphatic Index 59.07

Aromaticity 0.0795

Extinction Coeff. Reduced 70820.00

Extinction Coeff. Oxidized 71320.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192868 VERIFIED: NO

Provenance & Taxonomy

OrganismRaoultella electrica [Bacterium]

FamilyColicin/Bacteriocin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence