Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length193 amino acids

Chemical FormulaC943H1485N259O255S12

DescriptionStandard

        PMALAVAHEPMLLLAITDFVANSAAFTYFTAGALHRNISSDMLPRRFPLQLRTESMGGFSPQLQKRYPDHPMELHLSARKQPLFSCRPDALHGALFSSAEAFVVLPNATRVPVFLLSIDANVTGKPTISRNRLGGTVNLKGPACPMAPSACPMPGSGGLSVLQVKRLENLLKFSLWLFGVPWANSECCPHPVP
    

Molecular Weight20915.24 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.45

Net Charge (pH 7.4) 5.99

Charge Density (pH 7.0) 0.0334

GRAVY Index0.12

Hydrophobic Moment 0.57

Boman Index0.13

Instability Index58.87

Aliphatic Index 89.02

Aromaticity 0.0777

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7997.86

LogP -96.54

H-bond Donors 276.0

H-bond Acceptors 279.0

Rotatable Bonds 656.0

Heavy Atoms 1469.0

Ring Count 44.0

Amide Bonds 205.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009482 VERIFIED: NO

Provenance & Taxonomy

OrganismPedionomus torquatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria