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MYP_106268
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Standard
5 amino acids
C23H43N9O6
Standard
Sequence
ARPAK
Physicochemical Analysis
541.64 Da
11.00
1.79
1.61
0.3590
-1.28
0.81
-0.53
85.04
40.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
258.85
-2.72
9.0
8.0
16.0
38.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0172042 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0186407 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0304931 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
19.05 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0333843 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: 1H-Imidazol-1-yloxy, 2-[4-(2-ethoxy-2-oxoethoxy)phenyl]-4,5-dihydro-4,4,5,5-tetramethyl-, 3-oxide
Bio-Activity Profile
-
PaperSynthesis and Biological Activity of Nitronyl Nitroxide Containing Peptides Evidence URLhttps://doi.org/10.1021/jm050050k
RECORD: Rec_0355996 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: sulfonamide; Conjugated small molecule: p-Toluenesulfonamide
Bio-Activity Profile
-
PaperA new class of ¦Â-carboline alkaloid-peptide conjugates with therapeutic efficacy in acute limb ischemia/reperfusion injury PMID21396750 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21396750/
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