Peptide Database

Peptide NameRYamide 8

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC45H60N12O14

DescriptionStandard

        SGFYSNRY
    

Molecular Weight993.03 Da

Isoelectric Point (pI)8.31

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.25

Charge Density (pH 7.0) 0.0573

GRAVY Index-1.23

Hydrophobic Moment 0.19

Boman Index-0.18

Instability Index40.08

Aliphatic Index 0.00

Aromaticity 0.3750

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 452.93

LogP -5.31

H-bond Donors 17.0

H-bond Acceptors 15.0

Rotatable Bonds 29.0

Heavy Atoms 71.0

Ring Count 3.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0001800 VERIFIED: NO

Provenance & Taxonomy

OrganismOcypode ceratophthalma [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0157669 VERIFIED: NO

Provenance & Taxonomy

OrganismOcypode ceratophthalma [Animal]

FamilyNPY

Tax ID373423

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0237205 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0424954 VERIFIED: YES

Provenance & Taxonomy

OrganismOcypode ceratophthalmus [Animal]

FamilyRYamide

Tax ID373423

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour