Peptide Database

Peptide NameDAMGO

Function Ontology

Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier

Delivery / Targeting ▸ Drug delivery vehicle ▸ Drug delivery

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC24H35N5O9S

DescriptionStandard

        YAGME
    

Molecular Weight569.63 Da

Isoelectric Point (pI)4.60

Net Charge (pH 7.0)-1.23

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.2466

GRAVY Index-0.30

Hydrophobic Moment 0.16

Boman Index0.25

Instability Index55.36

Aliphatic Index 20.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 237.25

LogP -1.45

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 17.0

Heavy Atoms 39.0

Ring Count 1.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0134882 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Other ModsMethylation at phenylalanine

Bio-Activity Profile

Function

Opioid

MethodESI-LC−MS/MS

Half-LifeRat blood plasma (Intravenous), in vivo; 552 s

RECORD: Rec_0329916 VERIFIED: YES