Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length476 amino acids

Chemical FormulaC2349H3709N587O684S20

DescriptionStandard

        MLSSVIVVLMLLSCTCGENPAIQVVLNNKGLQYGKHAAAGWIQEKLEHITLPDIPGKVKIIFGTIDYTLTGVTILKCDFPEPSVEFLQDVPGFKASISGLSIALKGGWQTRFGIIHDGGTFNMAIFNVDVASVVHLGKDADGHPSVATNSCNAEIGNVDITFHGGASWIINPFVSHFKGRIRNEIQEKICPAVTESIESFENHLKAMNVSFDVDQVLSLDLPLTSEPVIEASSLNLGLKGEFYSIKTHKEPPFESQPFTMPEQPGYMLSVGMSDFTLNTASYGYYSADLLHVLITDSMIPPCSPVHLNTSSMGKFIPQLSKLFPDLLMNLMVYAKEAPEFTFKPNALTVDIKVIVKASAIAPNATQIPLFTLDVDSEFSSKLLIDGGSVKGSVTMNNLTLTLVASEVGSFKTDGLQNLAKMGVELILVKVQAILKNGIILPRLKHAQLVNSVLKMEEGFIAVFSDVEVFLTHRIFN
    

Molecular Weight51758.40 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-12.37

Net Charge (pH 7.4) -13.44

Charge Density (pH 7.0) -0.0260

GRAVY Index0.24

Hydrophobic Moment 0.65

Boman Index0.20

Instability Index34.45

Aliphatic Index 103.99

Aromaticity 0.0798

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28795.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393290 VERIFIED: YES

Provenance & Taxonomy

OrganismEtroplus suratensis (Green chromide) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria