Peptide Database

Peptide NameGonadotropin-inhibitory hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC68H107N17O15

DescriptionStandard

        SIKPFANLPLRF
    

Molecular Weight1402.68 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.46

Net Charge (pH 7.4) 1.25

Charge Density (pH 7.0) 0.1216

GRAVY Index0.30

Hydrophobic Moment 0.62

Boman Index0.15

Instability Index43.96

Aliphatic Index 105.83

Aromaticity 0.1667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 517.08

LogP -2.35

H-bond Donors 17.0

H-bond Acceptors 17.0

Rotatable Bonds 42.0

Heavy Atoms 100.0

Ring Count 4.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031456 VERIFIED: NO

Provenance & Taxonomy

OrganismSturnus vulgaris [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0291554 VERIFIED: YES

Provenance & Taxonomy

OrganismPhodopus sungorus [Animal]

FamilyGonadotropin-inhibitory hormone

Tax ID10044

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0329930 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide related peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0371188 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/