Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length363 amino acids

Chemical FormulaC1747H2738N458O529S13

DescriptionStandard

        GVNTATSWLQEKAKVTELPEISGNVDIGIGSVDYDLNGITVARLDMAQPDVAFQQGSGVRVDVTGVSVAVTGQWHTSFSIIRDSGSFDAALFDVGVSSVLLLGSDSQGRPSIQIDTCDSQIGDIQISFHGGASFIFQPFVDHFKGQIKGKIVDQICPSLNEGIGSLEAFLAAMNVSYHVDPSLFLDVPLTNAPLVQDSEVEFDLKGVFYSEADPLEPPFPSQEFPMARPADRMLAMAASEFCLNSYAYACLRAGLLQTLITDSMIPDMSPIRLNTSSFGALIPQLPKIFPNMLMELQVYAGEAPTVSLQPSVFALSLTAGIKASAVLPNSTLAPLFTLKLVREHRRRSPAAANSPRVRQPSHY
    

Molecular Weight39038.02 Da

Isoelectric Point (pI)4.76

Net Charge (pH 7.0)-13.71

Net Charge (pH 7.4) -14.34

Charge Density (pH 7.0) -0.0378

GRAVY Index0.12

Hydrophobic Moment 0.65

Boman Index0.15

Instability Index47.58

Aliphatic Index 94.57

Aromaticity 0.0799

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21680.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0257964 VERIFIED: NO

Provenance & Taxonomy

OrganismDenticeps clupeoides [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence