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MYP_106110
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Basic Information
Gaegurin-2 (Gaegurin 2; GGN2; Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
33 amino acids
C142H254N40O44S3
Standard
Sequence
GIMSIVKDVAKNAAKEAAKGALSTLSCKLAKTC
Physicochemical Analysis
3321.97 Da
9.51
3.74
3.50
0.1133
0.30
0.67
0.08
19.15
97.88
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1369.48
-15.80
50.0
51.0
118.0
229.0
0.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0207882 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Gaegurin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Serratia marcescens
200 μg/mL
MIC
PMID7999137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7999137/
RECORD: Rec_0211240 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Gaegurin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium
150 μg/mL
MIC
PMID7999137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7999137/
RECORD: Rec_0219025 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Gaegurin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
10 μg/mL
MIC
PMID7999137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7999137/
RECORD: Rec_0222565 VERIFIED: YES
Provenance & Taxonomy
Rana rugosa [Animal]
Gaegurin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial Antiparasitic
Staphylococcus epidermidis
10 μg/mL
MIC
PaperAntimicrobial peptides from the skin of a Korean frog, Rana rugosa.
RECORD: Rec_0223081 VERIFIED: YES
Provenance & Taxonomy
Glandirana rugosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic Antiprotozoal Anti-Gram-negative Anti-Gram-positive Hemolytic
Gram-negative and Gram-positive bacteria
PMID7999137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7999137/
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