Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length192 amino acids

Chemical FormulaC949H1511N265O258S11

DescriptionStandard

        PVALPMAREPMLLMAVTEFVANSAAFTYFAAGALRRNISNDMLPQRFPLQLRTKSMGVFSPQLQERYGDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNTTRVPVFLLNIDANVTGKPTITRNRLGGTVRLTGPACTVDSLPALCRAQGLPVPQVKRLETLLKFGLWLFGVPRANSECCPHPVP
    

Molecular Weight21113.48 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)6.28

Net Charge (pH 7.4) 5.92

Charge Density (pH 7.0) 0.0327

GRAVY Index0.07

Hydrophobic Moment 0.54

Boman Index0.10

Instability Index62.42

Aliphatic Index 92.97

Aromaticity 0.0729

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8223.05

LogP -99.35

H-bond Donors 284.0

H-bond Acceptors 279.0

Rotatable Bonds 666.0

Heavy Atoms 1483.0

Ring Count 40.0

Amide Bonds 208.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343562 VERIFIED: NO

Provenance & Taxonomy

OrganismNeopipo cinnamomea [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria