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MYP_106034
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Basic Information
Hp1239
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C77H116N16O18
Standard
Sequence
ILSYLWNGIKSIF
Physicochemical Analysis
1553.84 Da
8.59
0.76
0.55
0.0583
0.95
0.56
0.49
27.13
150.00
0.2308
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
558.11
-1.02
20.0
19.0
49.0
111.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0271980 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
26
CC50
PMID20443192;24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20443192/
RECORD: Rec_0306688 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
754296
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Entry inhibition
Inhibition of postentry in Vero cells
8.41±0.73 μM
EC50
Mammalian: 20 h; Yeast: 30 min; E. coli: >10 h
PaperInhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1. | Hong W, Li T, Song Y, Zhang R, Zeng Z, Han S, Zhang X, Wu Y, Li W, Cao Z. | Antiviral Res. 2014 Feb;102:1-10. | DOI:10.1016/j.antiviral.2013.11.013 | PMID:24315793 PMID24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24315793/
RECORD: Rec_0318621 VERIFIED: NO
Provenance & Taxonomy
Heterometrus petersii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antiviral
RECORD: Rec_0343808 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]; Arthropoda [Animal]
50557; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24315793/
RECORD: Rec_0347857 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
± 1
PMID20443192;24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20443192/
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