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MYP_106034
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Basic Information
Hp1239
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C77H116N16O18
Standard
Sequence
ILSYLWNGIKSIF
Physicochemical Analysis
1553.84 Da
8.59
0.76
0.55
0.0583
0.95
0.56
0.49
27.13
150.00
0.2308
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
558.11
-1.02
20.0
19.0
49.0
111.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008010 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
754296
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiviral Anti-HSV Entry inhibition
Herpes simplex virus type 1(HSV-1) | Vero cells
0.41±0.06 μM
EC50
Mammalian: 20 h; Yeast: 30 min; E. coli: >10 h
PaperInhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1. | Hong W, Li T, Song Y, Zhang R, Zeng Z, Han S, Zhang X, Wu Y, Li W, Cao Z. | Antiviral Res. 2014 Feb;102:1-10. | DOI:10.1016/j.antiviral.2013.11.013 | PMID:24315793 PMID24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24315793/
RECORD: Rec_0036112 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HSV-1
0.41 ± 0.06 μM
EC50
PMID24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24315793/
RECORD: Rec_0036967 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
intracellular herpes simplex virus type 1 (HSV-1) (Hong et al., 2014).
PaperInhibitory activity and mechanism of two scorpion venom peptides against herpes simplex virus type 1.
RECORD: Rec_0038116 VERIFIED: YES
Provenance & Taxonomy
Heterometrus petersii [Animal]
H
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
PaperAntiviral Res. 2014 Feb;102:1-10. | http://www.ncbi.nlm.nih.gov/pubmed/24315793 PMID24315793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24315793/
RECORD: Rec_0063570 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide; DSSP H 30.8%, E 0.0%, T 23.1%, C 46.2% [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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