Peptide Database

Peptide NameNoxaBH3

Function Ontology

Anticancer

Delivery / Targeting ▸ Drug delivery vehicle ▸ Drug delivery

Delivery / Targeting ▸ Targeting ligand ▸ Targeting

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC90H162N32O25S2

DescriptionStandard

        AACLRRIGDCVNLRQKLLN
    

Molecular Weight2156.58 Da

Isoelectric Point (pI)9.69

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.1461

GRAVY Index0.04

Hydrophobic Moment 0.67

Boman Index-0.18

Instability Index94.86

Aliphatic Index 128.42

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 965.41

LogP -10.05

H-bond Donors 36.0

H-bond Acceptors 30.0

Rotatable Bonds 75.0

Heavy Atoms 149.0

Ring Count 0.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0109378 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSource entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata

Other ModsConjugate type: sulfide; Conjugated small molecule: 6,6¡ä-Bis-bromomethyl-[3,3¡ä]bipyridine

Bio-Activity Profile

Function

Anticancer Drug delivery Targeting

TargetCancer cells