Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC550H876N144O169S

DescriptionStandard

        PDLSGHEKYGLGNVKYNISGIHVTAVEFPSASISLIPGAGIKLVIGNASLTIDTNWNIRTWIFKDKGRSTVYISKVFVTAIFSTTLDNTGYTSLSLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12241.77 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.92

Charge Density (pH 7.0) 0.0274

GRAVY Index0.04

Hydrophobic Moment 0.48

Boman Index0.14

Instability Index5.65

Aliphatic Index 97.46

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5030.01

LogP -56.29

H-bond Donors 181.0

H-bond Acceptors 175.0

Rotatable Bonds 404.0

Heavy Atoms 864.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077918 VERIFIED: NO

Provenance & Taxonomy

OrganismPsilopogon haemacephalus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria