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MYP_105979
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Basic Information
Abaecin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
39 amino acids
C213H294N54O49
Standard
Sequence
FVPYNPPRPGQSKPFPSFPGHGPFNPKIQWPYPLPNPGH
Physicochemical Analysis
4394.95 Da
10.00
2.93
2.62
0.0751
-1.03
0.41
0.06
57.70
27.44
0.1795
8480.00
8480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1538.31
-11.14
44.0
54.0
113.0
316.0
23.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184485 VERIFIED: YES
Provenance & Taxonomy
Bombus impatiens [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0328514 VERIFIED: YES
Provenance & Taxonomy
Bombus pascuorum [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Micrococcus luteus
PaperPubMed PMID: 9219367 PMID9219367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9219367/
RECORD: Rec_0370221 VERIFIED: YES
Provenance & Taxonomy
Bombus pascuorum [Animal]
Abaecin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperInsect Biochem Mol Biol. 1997 May;27(5):413-22. | http://www.ncbi.nlm.nih.gov/pubmed/9219367 PMID9219367 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9219367/
RECORD: Rec_0381089 VERIFIED: NO
Provenance & Taxonomy
Bombus pascuprum [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0416888 VERIFIED: YES
Provenance & Taxonomy
European bumblebee [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID10331812 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10331812/
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