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MYP_105968
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Basic Information
Dermaseptin-DA2
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
31 amino acids
C148H253N43O42S
Standard
Sequence
ALWKTLLKKVGKVAGKAVLNAVTNMANQNEQ
Physicochemical Analysis
3338.92 Da
10.18
3.79
3.60
0.1224
-0.14
0.69
0.03
1.06
103.87
0.0323
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1418.51
-14.11
47.0
47.0
117.0
234.0
2.0
36.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029651 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0045495 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
K. rhizophila ATCC 9341
0.8 μM
MIC
PaperCloning of cDNAs encoding new peptides of the dermaseptin-family.
RECORD: Rec_0053963 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Listeria monocytogenes SOR 100
100 μM
MIC
PaperCloning of cDNAs encoding new peptides of the dermaseptin-family.
RECORD: Rec_0068026 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Enterococcus faecalis CIP 103015
12.5 μM
MIC
PaperCloning of cDNAs encoding new peptides of the dermaseptin-family.
RECORD: Rec_0174728 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 6538 or ST 1065 or MRSA
12.5-25 μM
MIC
PaperCloning of cDNAs encoding new peptides of the dermaseptin-family.
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