‹ ›
MYP_105887
← PREVIOUS NEXT → BACK
Basic Information
MBD-4 (11-40)(P9)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV
Antiviral ▸ Anti-Coronavirus ▸ Anti-SARS-CoV-2
Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza A ▸ Anti-Influenza A virus
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Membrane / Ion-channel modulation ▸ Sodium channel modulation ▸ Sodium channel inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C144H227N47O35S5
Standard
Sequence
NGAICWGPCPTAFRQIGNCGHFKVRCCKIR
Physicochemical Analysis
3336.96 Da
9.41
4.80
4.47
0.1599
-0.07
0.60
-0.01
-1.33
55.33
0.1000
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1321.35
-13.90
51.0
46.0
105.0
231.0
7.0
32.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0194995 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anti-SARS-CoV-2
Virus
PMID26911565;32843628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26911565/
RECORD: Rec_0196036 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Defensin-derived peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Severe acute respiratory syndrome coronavirus
2.4 μg/mL
IC50
PaperA broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2 PMID32843628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32843628/
RECORD: Rec_0207093 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-SARS-CoV Replication inhibition
SARS-CoV | E6 cells
6.2 μg/mL
IC50
Mammalian: 1.4 h; Yeast: 3 min; E. coli: >10 h
PaperA broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2. | Zhao H, To KKW, Sze KH, Yung TT, Bian M, Lam H, Yeung ML, Li C, Chu H, Yuen KY. | Nat Commun. 2020 Aug 25;11(1):4252. | DOI:10.1038/s41467-020-17986-9 | PMID:32843628 PMID32843628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32843628/
RECORD: Rec_0225244 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anti-SARS-CoV-2 Cytotoxic
Madin-Darby canine kidney cells(TC50=380 μg/ml)
PMID26911565;32843628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26911565/
RECORD: Rec_0231830 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anti-SARS-CoV-2
Human Influenza A Virus H7N9:Inhibition of infection In MDCK cells
3.3 μg/mL
IC50
PMID26911565;32843628 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26911565/
FIRST PREV 1 ... 3 4 5 6 7 8 NEXT LAST
Showing 5 records on this page · Page 5 of 8