Peptide Database

Peptide NameEndothelin 1 [1-31]

Function Ontology

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC162H240N38O47S5

DescriptionStandard

        CSCSSLMDKECVYFCHLDIIWVNTPEHVVPY
    

Molecular Weight3632.19 Da

Isoelectric Point (pI)4.72

Net Charge (pH 7.0)-3.10

Net Charge (pH 7.4) -3.47

Charge Density (pH 7.0) -0.1000

GRAVY Index0.34

Hydrophobic Moment 0.34

Boman Index0.22

Instability Index47.40

Aliphatic Index 87.74

Aromaticity 0.1290

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1331.58

LogP -8.93

H-bond Donors 49.0

H-bond Acceptors 51.0

Rotatable Bonds 110.0

Heavy Atoms 252.0

Ring Count 9.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035314 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Neuropeptide