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MYP_105849
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Basic Information
XPF-SE4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
25 amino acids
C121H199N31O32
Standard
Sequence
GVWTTILGGLKKFAKGGLEALTNPK
Physicochemical Analysis
2600.06 Da
10.00
2.76
2.55
0.1104
0.04
0.61
0.19
7.21
97.60
0.0800
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1013.88
-8.01
35.0
35.0
87.0
184.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008897 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
80 μM
MIC
PaperHost-defense peptides in skin secretions of the tetraploid frog Silurana epitropicalis with potent activity against methicillin-resistant Staphylococcus aureus (MRSA)
RECORD: Rec_0100296 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
60 μM
LC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/22800690/ PMID22800690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800690/
RECORD: Rec_0130449 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
80 μM
MIC
RECORD: Rec_0156900 VERIFIED: YES
Provenance & Taxonomy
Silurana epitropicalis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-negative
Escherichia coli
40 μM
MIC
RECORD: Rec_0167133 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22800690 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800690/
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