Peptide Database

Peptide NameAlpha-defensin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC448H721N135O144S7

DescriptionStandard

        MRTLTILAAILLFTLQAQAESLQERADEVATQEQPGKDDQDLAVSFEENGLSTLRASGSQARRTCYCRTGRCYTPEFHSGKCVFNGRTYKLCCR
    

Molecular Weight10526.79 Da

Isoelectric Point (pI)7.58

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.17

Charge Density (pH 7.0) 0.0058

GRAVY Index-0.45

Hydrophobic Moment 0.56

Boman Index-0.13

Instability Index37.71

Aliphatic Index 68.62

Aromaticity 0.0745

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4578.13

LogP -55.20

H-bond Donors 168.0

H-bond Acceptors 153.0

Rotatable Bonds 354.0

Heavy Atoms 734.0

Ring Count 10.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0075418 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

FamilyDefensin

Tax ID9544

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function