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MYP_105807
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Basic Information
Act Beta-defensin 2 (18-40)[C12I,G14p,P15G,C-del] linear
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
22 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RXPGRTRQIGTIFPGRIKXRSW
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008398 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 18804
6 μM
MFC
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0024814 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655[LC = 5 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0050690 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 18804
12 μM
MFC
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0084019 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 18804
8 μM
MFC
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
RECORD: Rec_0113031 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 2,19
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 8530[LC = 5 microM]
PMID25791057 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25791057/
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