Peptide Database

Peptide NameBeta-defensin 10 (BNBD-10) (BNDB-10) (Neutrophil beta-defensin 10)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length62 amino acids

Chemical FormulaC301H508N96O75S8

DescriptionStandard

        MRLHHLLLLLLLVVLSSGSGFTQGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
    

Molecular Weight6928.37 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)8.61

Net Charge (pH 7.4) 8.21

Charge Density (pH 7.0) 0.1389

GRAVY Index0.40

Hydrophobic Moment 0.65

Boman Index0.06

Instability Index32.16

Aliphatic Index 114.68

Aromaticity 0.0484

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2749.41

LogP -26.09

H-bond Donors 107.0

H-bond Acceptors 94.0

Rotatable Bonds 230.0

Heavy Atoms 480.0

Ring Count 8.0

Amide Bonds 65.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0111027 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0387407 VERIFIED: YES