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MYP_105703
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C95H163N23O21S2
Standard
Sequence
FITLLLRKFICSITKKC
Physicochemical Analysis
2027.58 Da
9.85
3.74
3.50
0.2198
1.01
0.71
0.17
20.74
137.65
0.1176
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
729.57
-2.82
29.0
27.0
70.0
141.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150202 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0155684 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
Brevinin
8407
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial
PaperAntimicrobial peptides from amphibian skin: what do they tell us?
RECORD: Rec_0211149 VERIFIED: YES
Provenance & Taxonomy
European common [Animal]
Brevinin
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
11-17
Bio-Activity Profile
Antimicrobial
PMID10333736 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10333736/
RECORD: Rec_0259767 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0295946 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
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