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MYP_105682
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Basic Information
Nicomicin-1 (18-33)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C78H132N22O20S2
Standard
Sequence
IKNAKVCVYAVCVSHK
Physicochemical Analysis
1762.15 Da
9.31
2.82
2.54
0.1765
0.59
0.33
0.12
14.22
109.38
0.0625
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
690.11
-5.59
26.0
26.0
58.0
122.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150864 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli BL21
64 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0162702 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human red cells
40 μM
HC50
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0186527 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. licheniformis
8 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0237187 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli C600
64 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0271025 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Rhodococcus sp.
16 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
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