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MYP_105682
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Basic Information
Nicomicin-1 (18-33)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C78H132N22O20S2
Standard
Sequence
IKNAKVCVYAVCVSHK
Physicochemical Analysis
1762.15 Da
9.31
2.82
2.54
0.1765
0.59
0.33
0.12
14.22
109.38
0.0625
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
690.11
-5.59
26.0
26.0
58.0
122.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031298 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0039314 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 209P
16 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0044368 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
128 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0101145 VERIFIED: YES
Provenance & Taxonomy
Nicomache minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Acinetobacter baumanii
64 μM
MIC
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
RECORD: Rec_0117233 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30360541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30360541/
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