Peptide Database

Peptide NameParigidin-br1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC140H220N38O48S6

DescriptionStandard

        ADTTPCGESCVWIPCVSSIVGCSCQNKVCYQN
    

Molecular Weight3395.86 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.26

Net Charge (pH 7.4) -1.54

Charge Density (pH 7.0) -0.0394

GRAVY Index0.22

Hydrophobic Moment 0.31

Boman Index0.14

Instability Index19.15

Aliphatic Index 63.75

Aromaticity 0.0625

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1378.22

LogP -18.83

H-bond Donors 52.0

H-bond Acceptors 53.0

Rotatable Bonds 104.0

Heavy Atoms 232.0

Ring Count 5.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0379784 VERIFIED: YES

Provenance & Taxonomy

OrganismClitoria ternatea [Plant]

Structure & Mods

Confighead-to-tail cyclic, disulfide-constrained cyclotide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3 disulfide bonds (cyclic cystine knot); exact residue pairing unresolved in audited source

Bio-Activity Profile

Function

Insecticidal Antibacterial Antimicrobial Cytolytic

TargetEscherichia coli TOP10

Activity2.99 OD_ID (dimensionless)

MethodMex pooled growth assay at 4.5 h