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MYP_105640
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Basic Information
PP (De Novo Synthesis)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C95H134N28O15
Standard
Sequence
IHKFWRPGRWFKHI
Physicochemical Analysis
1908.26 Da
12.00
3.93
3.63
0.2809
-0.89
0.73
-0.11
110.34
55.71
0.2857
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
697.61
-0.42
26.0
21.0
58.0
138.0
9.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002156 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella Pulloru C79-13
4 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0017781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 43300
16 μM
MIC
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0029831 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human blood cells
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0059216 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
B. pyocyaneum ATCC 27853
4 μM
MIC
PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
RECORD: Rec_0061257 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
The cell viability of intestinal epithelial cells (IPEC-J2) induced by PP is 67
PaperShort Symmetric-End Antimicrobial Peptides Centered on beta-Turn Amino Acids Unit Improve Selectivity and Stability PMID30538681 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30538681/
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