Peptide Database

Peptide NameMotilin(1–12)ghrelin(6–28)

Function Ontology

Gastrointestinal bioactivity ▸ Gastrointestinal motility

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC189H304N58O51

DescriptionStandard

        FVPIFTYGELQRSPEHQRVQQRKESKKPPAKLQPR
    

Molecular Weight4204.79 Da

Isoelectric Point (pI)10.53

Net Charge (pH 7.0)4.85

Net Charge (pH 7.4) 4.58

Charge Density (pH 7.0) 0.1386

GRAVY Index-1.40

Hydrophobic Moment 0.39

Boman Index-0.38

Instability Index77.97

Aliphatic Index 52.86

Aromaticity 0.0857

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1797.40

LogP -17.23

H-bond Donors 60.0

H-bond Acceptors 57.0

Rotatable Bonds 139.0

Heavy Atoms 298.0

Ring Count 9.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050747 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyMotilin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Gastrointestinal motility

TargetGPR38 agonist activity

Activity0.01-0.009 μM

MethodEC50

Half-LifeIntravenouly injected in Sprague-Dawley rats, in vivo; 702 s

RECORD: Rec_0347497 VERIFIED: YES