Peptide Database

Peptide NameCyanea-RFamide 2

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC47H66N12O12

DescriptionStandard

        EPLWSGRF
    

Molecular Weight991.10 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-0.16

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) -0.0204

GRAVY Index-0.64

Hydrophobic Moment 0.14

Boman Index0.03

Instability Index62.42

Aliphatic Index 48.75

Aromaticity 0.2500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 393.45

LogP -1.94

H-bond Donors 14.0

H-bond Acceptors 12.0

Rotatable Bonds 28.0

Heavy Atoms 71.0

Ring Count 4.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020106 VERIFIED: YES

Provenance & Taxonomy

OrganismCyanea lamarckii [Animal]

FamilyCyanea-RFamide

Tax ID1307430

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0341094 VERIFIED: YES

Provenance & Taxonomy

OrganismCyanea lamarckii [Animal]

FamilyFMRFamide related peptide

Tax ID1307430

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0384272 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/