Peptide Database

Peptide NamePeptide 165

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC107H182N40O23

DescriptionStandard

        RPDKPRPYKPRKRPPRPVR
    

Molecular Weight2396.84 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.76

Net Charge (pH 7.4) 7.55

Charge Density (pH 7.0) 0.4083

GRAVY Index-2.66

Hydrophobic Moment 0.65

Boman Index-0.97

Instability Index59.17

Aliphatic Index 15.26

Aromaticity 0.0526

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1032.58

LogP -9.29

H-bond Donors 36.0

H-bond Acceptors 31.0

Rotatable Bonds 71.0

Heavy Atoms 170.0

Ring Count 8.0

Amide Bonds 18.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0193733 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-Term1-Amino cyclohexyl carboxylic acid

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus DSM 6247

Activity64 μg/mL

MethodMIC

RECORD: Rec_0308038 VERIFIED: YES