Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length105 amino acids

Chemical FormulaC531H847N161O159S7

DescriptionStandard

        MVRQRTATFSSSDWFWSHSSWVLQLKESGEKNGWLKKCYYGLGRCRKSCKEEEKKKEKCGKTLSCCLLSKNAKLSDFSPKPVTGEKWREREEREERGREGGGNKK
    

Molecular Weight12254.84 Da

Isoelectric Point (pI)9.58

Net Charge (pH 7.0)10.55

Net Charge (pH 7.4) 10.14

Charge Density (pH 7.0) 0.1005

GRAVY Index-1.28

Hydrophobic Moment 0.59

Boman Index-0.36

Instability Index45.58

Aliphatic Index 39.90

Aromaticity 0.0952

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5318.30

LogP -58.59

H-bond Donors 198.0

H-bond Acceptors 178.0

Rotatable Bonds 432.0

Heavy Atoms 858.0

Ring Count 18.0

Amide Bonds 109.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0095324 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence