Peptide Database

Peptide NameSLAY-screened peptide P1681

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC121H165N25O32S

DescriptionStandard

        CTKQYFSLDTSFWNWPTYLL
    

Molecular Weight2513.82 Da

Isoelectric Point (pI)5.83

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0126

GRAVY Index-0.23

Hydrophobic Moment 0.33

Boman Index0.18

Instability Index27.32

Aliphatic Index 58.50

Aromaticity 0.3000

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 930.12

LogP -5.11

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 73.0

Heavy Atoms 179.0

Ring Count 9.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367760 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/