Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC747H1170N224O223S6

DescriptionStandard

        MSRVQFKQRESTDAIFVHCSATKSSQNVGVREIRQWHKEQGWLDVGYHYIIKRDGTVEEGRDEMAVGSHAKGHNHNSIGVCLVGGIDDKGKFEANFTPAQMQSLRSLLVTLLAKYEGSVLRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight17049.04 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)2.19

Net Charge (pH 7.4) 1.48

Charge Density (pH 7.0) 0.0145

GRAVY Index-0.59

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index51.81

Aliphatic Index 72.91

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7250.38

LogP -76.56

H-bond Donors 257.0

H-bond Acceptors 239.0

Rotatable Bonds 576.0

Heavy Atoms 1200.0

Ring Count 27.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299257 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage CICC 80001 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic