Peptide Database

Peptide NameAdrenomedullin TrAM-5

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC185H298N60O61S2

DescriptionStandard

        APQRGCQVGTCQVHNLANKLYQIGRQGKDESTKVNDPQGY
    

Molecular Weight4402.84 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)1.86

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0466

GRAVY Index-1.06

Hydrophobic Moment 0.68

Boman Index-0.21

Instability Index23.27

Aliphatic Index 56.00

Aromaticity 0.0500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2012.04

LogP -26.96

H-bond Donors 68.0

H-bond Acceptors 66.0

Rotatable Bonds 148.0

Heavy Atoms 308.0

Ring Count 5.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019102 VERIFIED: NO

Provenance & Taxonomy

OrganismFugu rubripes,Takifugu rubripes [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide6-11

Bio-Activity Profile

Function

Neuropeptide Hormone